CLINICAL
RESEARCH AWARD, WINNER, 2004
48rd Korean Circulation Society Scientific
Session "Significance of unipolar
electrogram morphology at the earliest activation
site in ventricular tachycardia originated
from right ventricular outflow tract¡±
KOREAN SOCIETY OF
CIRCULATION, RESEARCH GRANT, 2004-2006
47rd Korean Circulation Society Scientific
Session
¡°Catheter Ablation of Ventricular Fibrillation
in vivo Swine Ventricles Treated With Beta-Blockers¡±
YOUNG INVESTIGATOR
AWARD, HONORABLE MENSION, 2003
2003 North American Society of Pacing and
Electrophysiology, Scientific Session
¡°Catheter ablation of ventricular fibrillation
in rabbit ventricles treated with beta-blockers¡±
AMERICAN HEART ASSOCIATION
FELLOWSHIP GRANT, 2002-2004
American Heart Association, Western Affiliate
#0225129Y
¡°Role of structural heterogeneity in electrical
remodeling during ventricular fibrillation¡±
YOUNG INVESTIGATOR
AWARD, HONORABLE MENSION, 2002
2002 American College of Cardiology Scientific
Session
¡°Mesenchymal stem cell injection induces
cardiac nerve sprouting and increased tenascin
expression in
a swine model of myocardial infarction¡±
YOUNG INVESTIGATOR
AWARD, WINNER, 1999
43rd Korean Circulation Society Scientific
Session
"Effects of action potential duration
on action potential duration restitution
kinetics and on the initiation
and maintenance of ventricular fibrillation"
KOREA UNIVERSITY
MEDICAL POSTGRADUATE SCHOOL, Seoul, South
Korea Ph.D. in Cardiology,
2000
~ Advisor: Professor Young Moo Ro, MD, PhD,
FACC.
~ Dissertation: "Effects of action potential
duration on action potential duration restitution
kinetics on the initiation and maintenece
of venticular fibrillation" Master
of Internal Medicine, 1994
~ Advisor: Professor Young Moo Ro, MD, PhD,
FACC.
~ Dissertation: ¡°Coronary angiographic findings
and risk factors in acute myocardial infarction
patients before and after age 50¡±
KOREA UNIVERSITY MEDCAL SCHOOL, Seoul,
South Korea
M.D. in Internal Medicine,
1991
Clinical Electrophysiology
UTAH VALLEY MEDICAL CENTER, Provo, UT, U.S.A.,
2003
Received specialized clinical electrophysiologic
training for catheter ablation of atrial
fibrillation and explored the clinical characteristics
of ligament of Marshall atrial tachyarrhythmia.
KOREA UNIVERSITY MEDICAL CENTER, 1999~2001
Received clinical cardiology fellowship
training for general cardiology (non-invasive
cardiology, echocardiography, and interventional
cardiology) and electrophysiology.
Research
CEDARS-SINAI MEDICAL CENTER, Los Angeles,
CA, U.S.A., 2001-2003
Investigated animal experiments about cardiac
nerve sprouting in mesechymal stem cell transplanted
swine myocardial infarction model. Studied
optical mapping and high density electrical
mapping studies with mapping guided excitable
gap pacing for control of ventricular fibrillation
and exploring ventricular fibrillation dynamics.
KOREA UNIVERSITY MEDICAL POSTGRADUATE
SCHOOL, 1994-2000
Conducted animal experiment about mechanism
of ventricular arrhythmia and effects of
antiarrhythmic agent using the isolated
right ventricular tissue of swine. Investigated
the importance of restitution
phenomenon in the mechanism of fibrillation
maintenance and antiarrhythmic or proarrhythmic
effects.
(From February 1996 to April 1999, participated
in the mandatory military service in South
Korean Marine Corps.)
KOREA UNIVERSITY MEDICAL POSTGRADUATE
SCHOOL, 1992-1994
Studied the coronary artery morphology in
patients with acute myocardial infarction.
Investigated specific morphology of coronary
artery culprit lesion along with age group
or symptom onset time.
KOREA UNIVERSITY MEDICAL SCHOOL, 1985-1991
Studied basic cardiac physiology and pathophysiology
in group of HEART and had an experience
of
animal experiments about arrhythmogenesis
in in vivo model.
Postgraduate training
CEDARS-SINAI MEDICAL CENTER, Los Angeles,
CA, U.S.A.
DIVISION OF CARDIOLOGY
Research fellow, 2001-2003
KOREA UNIVERSITY MEDICAL CENTER, Seoul,
South Korea
DIVISION OF CARDIOLOGY
Clinical fellow, 1999-2001
KOREA UNIVERSITY MEDICAL CENTER, Seoul,
South Korea
DIVISION OF INTERNAL MEDICINE
Resident, 1992-1996
KOREA UNIVERSITY MEDICAL CENTER, Seoul,
South Korea
Internship, March 1991-February 1992
2004~Present, KOREA
UNIVERSITY MEDICAL SCHOOL, Seoul, Korea
Division of EP Cardiology Assistant
Professor (Faculty Member)
2003
~ 2004, KOREA UNIVERSITY MEDICAL
SCHOOL, Seoul, Korea
Division of EP Cardiology
Clinical Associate
Professor
2001-2003, CEDARS-SINAI
MEDICAL CENTER, Los Angeles, CA, U.S.A.
DIVISION OF CARDIOLOGY
Research fellow,
1999 - 2001, KOREA UNIVERSITY
MEDICAL SCHOOL, Seoul, South Korea
Division of Cardiology
Cardiology Fellow
1997 - 1999, 2ND DIVISION
OF KOREAN MARINE CORPS
Medical Support Unit
Chief Medical Officer
(discharded as leutenant commander)
1996 - 1997, 2ND DIVISION
OF KOREAN MARINE CORPS
Medical Support Unit
Medical Officer in
Department of Internal Medicine
Peer Reviewed Papers(SCI)
1. Choi JI, Park SM, Park JS, Hong SJ, Pak HN, Lim DS, Kim YH, Shim WJ. Changes in Left Atrial Structure and Function After Catheter Ablation and Electrical Cardioversion for Atrial Fibrillation. Circ J. 2008;[In Press]
2. Choi JI, Pak HN, Kim YH. Hybrid epicardial and endocardial catheter ablation in patients with atrial fibrillation and suspicious left atrial thrombus. Circ J. 2008;[In Press]
3. Pak HN, Kim GI, Lim HE, Fang YH, Choi JI, Kim JS, Hwang C, Kim YH. Both Purkinje cells and left ventricular posteroseptal reentry contribute to the maintenance of ventricular fibrillation in open chest dogs and swine: effects of catheter ablation and cut and sew operation. Circ J. 2008;[In Press]
4. Shin SH, Park MY, Oh WJ, Hong SJ, Pak HN, Song WH, Lim DS, Kim YH, Shim WJ. Left atrial volume is a predictor of atrial fibrillation recurrence after catheter ablation. J Am Soc Echocardiogr. 2008;[In Press]
5. Nam MH, Roh KH, Pak HN, Lee CK, Kim YH, Lee KN, Cho Y. Evaluation of the Roche CoaguCheck XS handheld coagulation analyzer in a cardiac outpatient clinic. Ann Clin Lab Sci. 2008;38:37-40.
6. Choi JI, Pak HN, Kim YH. Recurrent syncope 20 years after mediastinal radiation therapy in a patient with breast cancer. Circ J. 2008.[In Press]
7. Pak HN, Kim JS, Shin SR, Lee HS, Choi JI, Lim HE, Hwang C, Kim YH. Is Empirical Four Pulmonary Vein Isolation Necessary for Focally Triggered Paroxysmal Atrial Fibrillation?: Comparison of Selective Pulmonary Vein Isolation vs. Empirical Four Pulmoanry Vein Isolation. J Cardiovasc Electrophysiol. 2008;[In Press]
8. Park MY, Shin SH, Oh WJ, Lim HE, Pak HN, Lim DS, Kim YH, Ro YM, Shim WJ. The prognostic implication of left atrial appendage mechanical reserve after cardioversion of atrial fibrillation. Circ J. 2008;72(2):256-61.
9. Pak HN, Hwang C, Lim HE, Kim JS, Kim YH. Hybrid epicaridal and endocardial ablation of persistent or permanent atrial fibrillation: new approach for difficult cases. J Cardiovasc Electrophysiol. 2007;18:917-923.
10. Lim HE, Pak HN, Ahn JC, Song WH, Kim YH. Torsade de pointes induced by short-term oral amiodarone therapy. Europace. 2006;8(12):1051-3.
11. Kim YH, Lim HE, Pak HN. Use of three dimensional mapping systems in the catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2006;17Suppl3:S16-22.
12. Pak H-N, Hong SJ, Hwang C, Kim Y-H. Twin AV node associated with interruption of inferior vena cava with azygos continuation. J Electrocardiol. 2006;39(4):400-3.
13. Lim HE, Pak H-N, Jung HC, Kim JS, Shim WJ, Kim Y-H. Electrocardiographic manifestations of cardiac metastasis in lung cancer. PACE 2006;29(9):1019-21.
14. Pak H-N, Hwang C, Lim HE, Kim JW, Lee HS, Ro YM, Kim Y-H. Electroanatomic characteristics of atrial premature beats triggering atrial fibrillation in patients with persistent versus paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol. 2006;17:818-24.
15. Pak H-N, Kim Y-H, Lim HE, Chou CC, Miyauchi Y, Fang YH, Sun K, Hwang C, Chen P-S. Posterior papillary muscle as an anchor to the reentrant wavefronts during ventricular fibrillation in open chest dogs and swine: effects of catheter ablation. J Cardiovasc Electrophysiol. 2006;17:777-783.
16. Lim HE, Pak H-N, Kim Y-H. Epicardial ablation of ventricular tachycardia associated with isolated ventricular non-compaction. PACE 2006;2006;29:797-799.
17. Lim HE, Pak H-N, Kim Y-H. Acute myocarditis associated with cardiac amyloidosis manifesting as transient complete atrioventricular block and slow ventricular tachycardia. Internat J Cardiol. 2006;109:395-397.
18. Miyauchi M, Qu Z, Miyauchi Y, Zhou SM, Pak H-N, Mandel WJ, Fishbein MC, Chen PS, Karagueuzian HS. Chronic nicotine in hearts with healed ventricular myocardial infarction promotes atrial flutter that resembles typical human atrial flutter. Am J Physiol Heart Circ Physiol. 2005;288:H2878-86.
19. Lim HE, Pak H-N, Shin SH, Cho SB, Sun K, Kim Y-H. Collagen plug device-related femoral artery complication visualized by femoral angiography. Internat J Cardiol. 2005;106:128-129.
20. Pak H-N, Lim HE, Kim Y-H. Atrial tachycardia originated from coronary sinus ostium dissociated with fibrillation activity inside persistent left superior vena cava. Heart Rhythm. 2005;2:33.
21. Liu Y-B, Pak H-N, Lamp S, Okuyama Y, Hayashi H, Wu T-J, Weiss J, Chen P-S, Lin S-F. Co-existence of two types of ventricular fibrillation during acute regional ischemia in rabbit ventricles. J Cardiovasc Electrophysiol. 2004;15(12):1433-1440.
22. Okuyama Y, Pak H-N, Miyauchi Y, Liu YB, Chou CC, Hayashi H, Fu KJ, Kerwin WF, Kar S, Hata C, Karagueuzian HS, Fishbein MC, Chen P-S, Chen LS. Nerve sprouting induced by radiofrequency catheter ablation in dogs. Heart Rhythm. 2004;1:712-717.
23. Pak H-N, Hong SJ, Hwang GS, Lee HS, Park SW, Lim DS, Shim WJ, Ro YM, Kim Y-H. Spatial dispersion of action potential duration restitution kinetics predicts the induction of ventricular tachycardia/fibrillation in humans. J Cardiovasc Electrophysiol. 2004;15(12):1357-63.
24. Chou C-C, Zhou S, Miyauchi Y, Pak H-N, Okuyama Y, Fishbein MC, Karagueuzian HS, Chen P-S: Effects of procainamide on electrical activity in the thoracic veins and the atria in a canine model of sustained atrial fibrillation. Am J Physiol. 2004 ; 286:H1936-H1945.
25. Pak H-N, Okuyama Y, Oh Y-S, Hayashi H, Liu Y-B, Chen P-S, Lin S-F. Improvement of Defibrillation Efficacy with Spatiotemporally Controlled Shocks in Rabbit Ventricles. J Cardiovasc Electrophysiol. 2004;15:581-587.
26. Pak H-N, Oh Y-S, Liu Y-B, Lin S-F, Chen P-S. Catheter Ablation of Ventricular Fibrillation in Rabbit Ventricles Treated With Beta-Blockers. Circulation. 2003;108:3149-56.
27. Pak H-N, Liu Y-B, Hayashi H, Okuyama Y, Chen P-S, Lin S-F. Synchronization of ventricular fibrillation with real-time feedback pacing: Implication to low-energy defibrillation. Am J Physiol. 2003;285(6):H2704-11.
28. Pak H-N, Qayyum M, Lai AC, Kim DT, Hamabe A, Miyauchi Y, Lill MC, Frantzen M, Takizawa K, Chen LS, Fishbein MC, Sharifi BG, Chen P-S, Makkar R. Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a swine model of myocardial infarction. J Cardiovasc Electrophysiol. 2003;14:841.
29. Okuyama Y, Miyauchi Y, Park AM, Hamabe A, Zhou S, Hayashi H, Miyauchi M, Omich C, Pak H-N, Brodsky LA, Mandel WJ, Fishbein MC, Karagueuzian HS, Chen P-S. High Resolution Mapping of the Pulmonary Vein and the Vein of Marshall During Induced Atrial Fibrillation and Atrial Tachycardia in a Canine Model of Pacing-Induced Congestive Heart Failure. J Am Coll Cardiol. 2003;42:348-60.
30. Hamabe A, Okuyama Y, Miyauchi Y, Zhou S, Pak H-N, Karagueuzian HS, Fishbein MC, Chen P-S. Correlation between anatomy and electrical activation in canine pulmonary veins. Circulation 2003;107:1550
31. Hayashi H, Wang C, Miyauchi Y, Omichi C, Pak H-N, Zhou S, Ohara T, Lin S-F, Fishbein MC, Mandel WJ, Chen P-S, Karagueuzian HS: Ageing-related increase to inducible atrial fibrillation in the rat model. J Cardiovasc Electrophysiol. 2002;13:801-808.
32. Byung-Soo Kim, Young-Hoon Kim, Gyo-Seung Hwang, Hui-Nam Pak, Sang Chil Lee, Wan Joo Shim, Dong Joo Oh, Young Moo Ro. Action potential duration restitutin kinetics in human atrial fibrillation. J Am Coll Cardiol. 2002;39:1329-36.
33. Kim KJ, Shim WJ, Jung SW, Pak H-N, Lee SJ, Song WH, Kim YH, Seo HS, Oh DJ, Ro YM. Relationship between T-wave normalization on exercise ECG and myocardial functional recovery in patients with acute myocardial infarction. Korean J Intern Med. 2002;17(2):122-30.
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2004 Korea University, Cardiovascular Center. All Rights Reserved.
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